Featuring Polydeoxyribonucleotide + P.E.T.® Technology
🧬 What is PDRN?
Polydeoxyribonucleotide (PDRN) is a biologically active DNA fragment extracted from salmon sperm that has shown remarkable results in skin regeneration and healing therapies. Clinically studied and used in regenerative medicine, PDRN is known for its ability to:
• Stimulate cellular renewal
• Enhance tissue repair
• Activate wound healing pathways
• Promote angiogenesis (formation of new blood vessels)
PDRN acts through the A2A adenosine receptor pathway, which stimulates fibroblast activity, leading to increased collagen and elastin synthesis. It also provides nucleotide precursors that help rebuild damaged DNA in skin cells — making it a powerful anti-aging and post-procedure recovery agent.
Because of its high molecular weight, PDRN is traditionally delivered via injection in clinical settings. However, SESHA has changed that.
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🔬 The SESHA Advantage: P.E.T.® Delivery System
While most topical PDRN serums remain limited by skin penetration issues, SESHA’s proprietary P.E.T.® (Permeation Enhancement Technology) changes the game.
• P.E.T.® creates temporary micro-channels in the stratum corneum, allowing large molecules like PDRN to penetrate the skin barrier without needles.
• It delivers active ingredients to deeper layers, where they stimulate true cellular regeneration, not just surface hydration.
• The result is a clinical-grade performance in a topical formulation.
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🌿 Key Benefits of MesoBotanica PDRN Serum
• Accelerates healing from microneedling, peels, and laser treatments
• Restores damaged skin and improves texture, tone, and elasticity
• Calms redness and inflammation with anti-inflammatory action
• Supports DNA repair and cellular longevity
• Boosts collagen synthesis and overall skin firmness
• Improves skin resilience against environmental stress and aging
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💧 Ideal For:
• MesoBotanica Nano Pen infusion treatments
• Post-procedure recovery protocols
• Sensitive, aging, or damaged skin types
• Clients seeking non-invasive rejuvenation with visible and lasting results